“Quality of life of the general population during the COVID-19 pandemic” Objective: To examine the impact of the COVID-19 pandemic on the quality of life of the general population and to compare it by age, sex, level of education and place of residence. Methods: The respondents of this research are adults who have voluntarily agreed to fill in the online survey questionnaire. An anonymous questionnaire was used as a research instrument, which was according to the read literature formulated for the needs of this research and which was created online (Google forms /surveys) and posted on the online platform. The research was conducted in the period from March 13 until March 26, 2021. Results: 605 respondents participated in the research, of which 553 (91.4%) were females, 243 (40.2%) were aged 31 to 40 years. The COVID-19 pandemic strongly affects the quality of the general population with M = 29,145; a higher value of the results means a lower quality of life for the respondents during the COVID-19 pandemic. Conclusion: The COVID-19 pandemic strongly affects the quality of life of the general population with M = 29,145; a significant difference was found in the assessment of the quality of life of respondents in the COVID-19 pandemic in respondents divided by gender (T = -2,308; P = 0.02), in the manner that female respondents assessed that their quality of life was significantly lower than male respondents, with regard to place of residence, there is a significant difference (T = -1,963; P = 0.04), in that respondents living in the village assess their quality of life significantly worse than respondents in the city during the COVID-19 pandemic.