Aim of the research: To examine the quality of life and self-esteem of women, differences in quality of life and self-esteem in relation to demographic variables, actions of medical staff and the environment, habits and experiences after pregnancy loss. Study design: Cross-sectional study. Subjects and methods: 102 women who experienced pregnancy loss participated. Anonymous, voluntary survey, conducted online in August 2024. Sociodemographic questionnaire, WHOQOL-BREF, and Rosenberg's self-esteem scale were used. Results: Women are satisfied with the overall quality of life and general health. The highest quality of life is in the social relations subscale, the lowest is in the environment subscale. Most women have high self-esteem. Married and unmarried women have better overall quality of life, and women with low self-esteem have worse overall quality of life and physical health. Rural women have marginally higher self-esteem, and employed women have higher self-esteem than the unemployed. Women aged 50 and over and women with low self-esteem are more indecisive in that they had support from their partner and family after they had lost a pregnancy. With women with low self-esteem, people talk less about the loss and their employers are less sensitive. Women with a high level of self-confidence have more support from their environment. Women with low self-esteem more often have to return to their habits and work duties after 3 months of the loss. Conclusion: A lower quality of life and level of self-esteem are present in respondents who are not married and unmarried, are 50 years old and older, and who have lower levels of support from their partners, family, and environment. It is necessary to encourage the development of awareness of the importance of supporting women after pregnancy loss.