Objectives: To examine the dynamics of the consumption of addictive substances among first- and second-year graduate nursing students, as well as to examine whether there is a connection between alcohol consumption and the development of alcohol dependence, and whether there is a connection between the consumption of drugs other than alcohol among first- and second-year nursing students and the risk of developing addiction. Study design: A cross-sectional study. Respondents and methods: 99 first- and second-year graduate nursing students participated in this research. The research was conducted through anonymous questionnaires that were distributed to respondents via the Google Forms platform, and completing the survey was considered voluntary consent to participate. The research was conducted in May and June 2023. Results: 88 respondents (88.89%) had an AUDIT score of less than 8 points, which is 8 times more than subjects with an AUDIT score of 8 or more points (n=11; 11.11%), and after the examination, it was determined that the majority of students do not show the characteristics of risky or harmful drinking, that is, possible alcohol addiction (χ2=59.89; P<0.001). Examining the risk of taking drugs found that the largest number of respondents (n=93; 93.94%) belonged to the low-risk category (0–7 points), while a high level of risk was present in one respondent (1.01%), and it was determined that most students have a low level of risk (χ2=163.88; P<0.001). Conclusion: Based on the results obtained through the AUDIT questionnaire, it can be concluded that the majority of students do not show the characteristics of risky or harmful drinking, as well as the possibility of alcohol addiction. Based on the results of the DUDIT questionnaire, the majority of students fall into the category of low risk for developing drug addiction.