Introduction: The digestive system functions as one complex organic system in man. If we consider the numerous functions and tasks of the digestive system, we can conclude that only one disorder of the digestive system can lead to serious conditions of the human body. Procedures: The necessary information and data for the preparation of the final paper were requested in the printed literature of mostly domestic authors, articles that are available on the Internet of scientific and professional topics. General search engines and scientific databases were used to search for articles. Topic overview: Bleeding from the upper part of the digestive system is a health condition with various etiologies and presentations. It is defined as a loss of blood originating around the esophagus, stomach or duodenum. Bleeding occurs in the upper digestive tract as melena or hematemesis. Bleeding in the lower part of the digestive system is found in the jejunum, ileum, and colon where the highest percentage of bleeding is located. The causes of bleeding that lead to bleeding are inflammatory bowel diseases like ulcerative colitis, angiodysplasia and hemorrhoids. Conclusion: Bleeding in the digestive system comes from a variety of causes as a result of an unhealthy lifestyle, genetic predisposition, or the use of drugs that damage the mucosa. Acute bleeding requires urgency and expertise of the medical team, and chronic bleeding in the digestive system leads to gradual anemia. The role of the nurse is crucial as she takes the patient on the path to health.