Objectives: The objectives of this study are to determine whether there is a difference in attitudes and knowledge of people vaccinated with Comirnaty and Spikevax vaccine about COVID-19 disease by gender, age, education, place of residence, financial status and type of vaccine they received and to determine whether there is a correlation between the attitudes and knowledge of persons vaccinated with Comirnaty and Spikevax vaccine about COVID-19 disease with gender, age, level of education, place of residence, financial status and type of vaccine they received. Study design: cross-sectional study Participants and methods: Subjects of this study are persons vaccinated with Comirnaty and Spikevax vaccines at the Brod-Posavina County Public Health Teaching Institute. Results: 206 respondents participated in the research, of which 51.9% were female. Furthermore, the attitudes of people vaccinated with Comirnaty and Spikevax vaccine about COVID - 19 disease had a low positive correlation with the place of residence of the subjects (r = 0.142; P = 0.04), subjects’ age (r = 0.332; P <0.001) and the type of vaccine received. r = 0.155; P = 0.02), and a low negative correlation with the economic status of the respondents. Respondents' knowledge on Covid 19 has a low positive correlation with respondents' level of education, i.e. the higher the level of education, the better the respondents' knowledge on COVID-19 disease. Conclusion: There is no difference in the attitudes of people vaccinated with Comirnaty and Spikevax vaccine on COVID-19 disease according to gender and level of education. There is a difference according to age, place of residence, financial status and type of vaccine received. There is no difference in the knowledge of persons vaccinated with Comirnaty and Spikevax vaccine on COVID-19 disease by sex, place of residence, financial status and type of vaccine received, and there is a difference according to age and educational status.