Aim of the research: to examine the opinions of health professionals about vaccination against disease COVID-19 Study outline: cross-sectional study Examinees and methodology: this study involved health professionals from OB "Dr. Josip Benčević ”in Slavonski Brod. 181 examinees participated, in the period from December 2021 to March 2022. An unstructured survey questionnaire was used during the research. The questions were closed-ended. The questionnaire contains 21 questions, of which 7 are demographic and 14 are questions related to the opinion of health professionals about vaccination against COVID-19. Results: out of 181 subjects, 124 (68.51) recovered from COVID-19. Ninety of them (72.58) suffered a mild clinical picture. 150 (82.87) examinees think that children should not be vaccinated and 128 (70.72) examinees think that pregnant women should not be vaccinated. Most examinees think that elderly should be vaccinated, 68 of them (37.57). Ninety (50.28) examinees think that the vaccine protects against infection.149 (82.32) examinees were vaccinated against COVID-19. One of the most common reasons why examinees were vaccinated is because after vaccination the symptoms of the disease are milder, 70 (46.98) and to protect family and patients, 54 (36.24). One of the most common reasons why examinees did not get vaccinated is that the vaccine has not been sufficiently clinically tested, 21 (65.63) and because even after vaccination a person can become infected, 19 (59.38). Conclusion: most examinees think that children and pregnant women should not be vaccinated. Most were vaccinated against COVID-19. Most think that elderly should be vaccinated. Examinees were mostly vaccinated because the symptoms of the disease are milder after vaccination and to protect family and patients, and those who were not were not vaccinated chose to do so because the vaccine has not been sufficiently clinically tested and because it can be infected after vaccination.