THE RESEARCH AIM: To determine the frequency of surgical wound infections in children treated at the Department of Paediatric Intensive Care Medicine of the Zagreb Clinical Hospital Centre and to determine clinical outcomes. STUDY DRAFT: A cross-sectional study. SUBJECTS AND METHODS: The research included a total of 136 respondents who, due to the need for surgical intervention, were hospitalized at the Department of Paediatric Intensive Care Medicine of the Clinical Hospital Centre Zagreb in the period from 1 June 2021 until 31 December 2021 The data from the Hospital Information System were used. RESULTS: The research included 136 respondents aged from 15 days to 23 years. The percentage of male children with infected wounds compared to those with sterile wounds is slightly lower, and the percentage of female children is slightly higher, but this difference was not statistically significant (P=0.9534). Out of 136 subjects who underwent various surgical procedures, 38 of them ( 27.9%) had a wound infection. The most common causative agents of wound infections are Enterobacter cloacae and Klebsiella oxytoca, each confirmed in 18.4% of wound swabs, then Proteus mirabilis confirmed in 15.8% of swabs, and Corynebacterium glucuronolyticum and Pseudomonas aeruginosa each confirmed in 10.5% of swabs. The other causative agents are represented from 2.6 to 7.9%. CONCLUSION: Analysing the results, it can be concluded that the infection developed in as many as 27.9% of operated children, which is statistically significantly more than expected. Positive smears were most often in the case of diagnoses of bile duct atresia, atrial septal defect, pulmonary artery stenosis and atrioventricular septal defect, and the most common causative agents were Enterobacter cloacae, Klebsiella oxytoca and Proteus mirabilis. Multiple regression analysis did not confirm a statistically significant association between the incidence of infection and predictor variables such as gender, age and diagnosis.