The aim of the research The aim was to test the advantages of the intraoperative use of medical devices for autotransfusion, in order to reduce the need for the use of homologous blood. The aim was to find out the number of patients who used autotransfusion in liver transplant operations, concerning their age, sex, diagnosis and the needs for the blood volume replacement. The interdependence between the diagnosis and the age and the sex of the respondents needed to be analysed, too. In addition to that,the aim was to examine the interdependence of age and the sex to the total blood loss, the homologous blood intake and the amount of blood return, and also the connection of blood loss and blood return to the diagnosis. The respondents and the methods The medical files and the data from the Clinical Information System( CIS), based on the 84 liver transplant patients in the period between January 1, 2021 - December 31, 2021 at the Clinical Hospital ' Merkur', were used in a retrospective study. The ethical approval for the research was granted first , and the study was conducted considering all ethical principles. The results In the examined group of 30 patients was evidently used autotransfusion, and 25 of them were liver cirrhosis patients. The autotransfusion was not used with patients who primarily suffer from HCC( Hepatocellular Carcinoma), since the autotransfusion is still contraindicated in liver cirrhosis patients in the Republic of Croatia. There is not any significant connection between the diagnosis and the sex of patients to it. The study proved a significant difference in the homologous blood intake with the patients who received an autotransfusion. There was an evident and a significant interdependence between the diagnosis and the age of patients in the examined group. The conclusion The results of this study indicate a reduced need for the use of homologous blood with all the respondents who received an autotranfusion in liver transplant operations, due to the use of the intraoperative transfusion.