Aim of the research: To examine the opinion of Nursing students on the protection of patient confidentiality in the era of digitization and whether there are differences in relation to age, gender, year of study, work status and completed secondary education. Study design: Cross-sectional study. Respondents and methods: The research sample consisted of 176 respondents. The respondents were students of undergraduate and graduate studies in Nursing, Faculty of Dental Medicine and Health, Osijek. The data was collected using an anonymous survey questionnaire designed and adapted exclusively to the needs of the research. Results: Female respondents, aged 30-34 and in graduate studies, use Facebook and Instagram, while male respondents, aged 19-24 and in undergraduate studies use multiple networks. Undergraduate students check networks weekly, graduate students daily. Women respect privacy more, provide information and do not give priority to the better-dressed patients, interact with families, close the door during procedures. Men talk privately about patients less, do not search documentation, do not comment on appearance, and rarely give preference to the better-dressed. Respondents aged 30-34 do not pay more attention to young people and interact with their families more often, those aged 19-24 do not comment on patients’ appearance and respect the privacy of disabled patients more. Respondents of the first year of undergraduate studies do not give more attention to young people and do not prefer the better-dressed patients, do not comment on appearance, do not search the networks for information, do not take photos, do not publish photos of patients. All respondents always respect the privacy of disabled patients. Conclusion: Students have a developed awareness of protecting patient confidentiality, are guided by ethical principles, use social networks responsibly and perform diagnostic and therapeutic procedures.