Aim of the research: To examine the opinion of nursing students regarding the impact of social media on health, differences and connections in relation to personal characteristics, sources of information and frequency of use. Study design: Cross-sectional study. Respondents and methods: 104 nursing students were included. The questionnaire was distributed online, and it took about 10 minutes to complete it. The research is voluntary, anonymous and conducted during April 2024. Results: Respondents use social media for personal purposes. They believe that social media in medicine and healthcare raises ethical issues and issues of personal data protection, and that excessive use can lead to development of addiction. Women are more likely to believe that social media has an impact on reducing stigmatization, but that it can result in reduced self-esteem, social isolation, and development of depression. The older the respondents are, the less they agree that social media provide new opportunities for learning and sharing knowledge about health. Respondents who get information about health through social media are more likely to believe that the information posted is verified, accurate and based on evidence. Respondents who get information from professional literature are more likely to believe that social media has an impact on reducing stigmatization, the development of eating disorders, physical inactivity, dissatisfaction with one's own appearance, unwanted outcomes, reduced self-esteem, social isolation, and depression. Higher frequency of social media usage is associated with a higher level of agreement that social media are used for personal purposes and that they provide new opportunities for learning and sharing knowledge about health. Conclusion: By sensible use of social media and by considering risks, healthcare professionals can improve patient outcomes and the exchange of knowledge about health.