Aim: The aim of the research was to examine the knowledge and attitudes of dental medicine final-year students about drug-induced osteonecrosis of the jaw at the Faculty of Dental Medicine and Health in Osijek, and to relate them to the level of study. Respondents and methods: The research was conducted on students of the fourth, fifth and sixth year of dental medicine at the Faculty of Dental Medicine and Health in Osijek. The research was conducted during August 2024 through a computerized anonymous survey questionnaire using the online application "Microsoft Forms" (Microsoft Forms, Microsoft Inc., USA). The questionnaire consisted of 27 questions. The first group of questions was related to demographic data (age, gender, and year of study), the second group of questions included students' knowledge and information about MRONJ, and the third group included attitudes in the treatment of such patients. Results: In the research participated 56 respondents. Most of the respondents, 30 of them (54 %), attended the 6th year of study. More than 90 % of respondents are familiar with bisphosphonates. Half of the respondents rated their knowledge about bisphosphonates as good (3). Osteonecrosis was cited as the main complication during bisphosphonate therapy by 80 % of respondents. Sixty-three percent of respondents are not familiar with the classification of MRONJ. The majority of respondents (> 60 %) indicated the installation of a dental implant and tooth extraction as complications that they would not perform without prior consultation with specialists in patients on antiresorptive therapy. More than half of the students were not confident in indicating invasive dental procedures in patients on oral bisphosphonate therapy. The level of studies influenced the self-assessment of students in the prevention of MRONJ. Conclusion: The students were familiar with the problem of drug-induced osteonecrosis of the jaw, but showed insufficient knowledge in the field of appropriate prevention and treatment. Additional educational efforts and studies of student populations are needed in order to improve the prevention of MRONJ in risk groups.