Aim of the research: To test the motivation of people from Nova Gradiška district for COVID- 19 vaccination given their age, gender, marital status, place of residence, level of education, work status, and to test their motivation given their awareness of vaccination against COVID- 19, the availability of the vaccines against COVID-19, the fear of death or severe consequences of COVID-19 disease, and to learn about the reasons why they have received the COVID-19 vaccine. Study outline: The research has been organised as a cross sectional study. Examinees and methods: 126 patients of both gender, who met the requirements to participate in the study, have participated in the research: participants older than 18 years of age, vaccinated against COVID-19 with the signed informed consent. All persons involved in the research have been informed of the purpose and aim of this research both in writing and orally, and the participation in this research was voluntary, anonymous and confidential. To assess the motivation of people from Nova Gradiška district for COVID-19 vaccination, a questionnaire containing age, gender, marital status, level of education and questions concerning the motivation of people from Nova Gradiška district for COVID-19 vaccination, was created and used for this research. Results: A significantly higher motivation for vaccination was noticed among the examinees aged 56 and older, among married examinees and among retired examinees and housewives. Examinees who had informed themselves orally with their doctors or nurses were more motivated for vaccination. Examinees who weren't afraid of the COVID-19 vaccination sideeffects were also more motivated. Examinees who vaccinated themselves for their own health and the health of their families were also more motivated. Conclusion: Gender, place of residence and level of education do not influence the motivation of people for COVID-19 vaccination.